ANNUAL REPORT - 2018
DEPARTMENT OF PATHOLOGY
Department of Pathology has been an integral part of BP Koirala Memorial Cancer Hospital, since its
inaugurat on as a Day Care Center on 11 October 1995. Our moto is to provide cut ng edge diagnost c
pathology services while achieving qualitat ve outcomes in pathology research and educat on.
Pathology services were started with rout ne laboratory tests, Fine Needle Aspirat on Cytology and Bone
marrow examinat on. Afer indoor services were started on 20
July 1999, pathology services were also
expanded. Now we have our own separate two-storied building allocated for Department of Pathology.
Responsibilit es of the department are immense and paramount to the services of the cancer pat ent in
rendering a final diagnosis, assist in evaluat on of prognost c factors, facilitate support ve services during
treatment and help in assessment of recurrences or persistence of disease. The scope and volume of the
clinical services provided by the Pathology Department have cont nued to grow steadily in the past years.
We are very proud to be associated with longstanding excellence in pat ent care, educat on and research; and
cont nue to build on these rich tradit ons into the future.
Department of Pathology serves as a core facility for the BP Koirala Memorial Cancer Hospital and has different
units allocated for different invest gat on modalit es. Our department has been pioneer in Nepal to start Flow
cytometry, Immunohistochemistry and Cytogenet c studies, which have been regularly done in our Inst tute.
Histopathology unit: Minor and Major biopsies for histopathological examinat on and diagnosis.
Special stains, when required, are also carried out. 18% more than that of 2017.
Total Histopathology cases:
Cytopathology unit: Fine Needle Aspirat on Cytology along with USG and CT guided aspirat ons,
Exfoliat ve cytology (Cervical Papanicolau Smear, Bronchial brushing, Bronchioalveolar lavage, Urine
barbotage); Body Fluid Cytology (Pleural fluid, Peritoneal fluid, Cerebrospinal fluid) invest gat ons are
Cervical Liquid Based Cytology
Cytology of body fluid and exfoliat ve cytology:
Fine needle aspirat on (FNA):
Hematology unit: Rout ne Tests include Blood Hemogram, Total Leukocyte count, and Different al
count done on daily basis by fully automated five-part hematology analyzers(Sysmex XN1000).
Peripheral Blood smear examinat on; Bone
marrow aspirat on and examinat on for
hematological abnormalit es are available.
Total Hematology cases:
Bone Marrow Aspirat on:
Peripheral Blood Smear:
Biochemistry unit: Fully automat c Biochemical
(Dimension RxL, Siemens) is in
operaton to carry out biochemical tests. Total
ANNUAL REPORT - 2018
mmunoserology Unit: Fully Automated Roche ecobas 411 analyzer is being used to perform tumour
Total Cases: 14601
5. Microbiology unit: Culture and sensit vity are
performed by Bactec Culture System along
with Serological tests on a daily basis. Various
samples like blood, urine, pus, sputum, body
fluid(pleural fluid, bronchial wash, CSF, bile, etc)
and Swab culture and sensit vity tests(Total 999
cases) are performed. Special stain viz: Gram’s
Stain-120, Stain in AFB- 802, KOH Preparat on
-29, ASO t tre -107, CRP -672 and Mantoux test -
101 cases are done in 2018.
Immunohistochemistry unit: This unit was
2009. Our panel
16 markers, with complete breast
panel for diagnost c purposes. In 2018 a total of
769 IHCs are reported
6. Flowcytometry unit: Flow cytometry was started on 1 January 2010. Four colour BD FACS system is in
use for diagnosis of hematological and lymphoid malignancies. In 2018, 8 cases are examined.
7. Emergency Lab: Twenty four hour laboratory services are provided through the emergency lab unit
located within the premises of our department. Recently a new emergency lab is situated in the new
ward building for effect ve emergency services.
8. Plateletpheresis: A Fresenius Kabi Pheresis is under use to perform plateletpheresis and a total of 81
cases are done in 2018.
ANNUAL REPORT - 2018
Being one of the prime diagnost c department, our most significant roles is in the teaching of the next
generat on of pathologists and laboratory technical staff.
Training of MD Pathology students from different Medical Colleges
Training and discussions of general and clinical pathology were delivered to BMLT, CMLT and
Lectures offered on different topics to MN, BNS, BMLT,CMLT and AMLT students
Dr. Ranjan Raj Bhata: Three months training on Cytogenet c at ATREC, Mumbai (2018 Nov 12-
Dr. Greta Pandey: Part cipat on and oral presentat on on “ Histopathological spectrum of skin
tumor at tert ary cancer centre in Nepal” at Internat onal Society of Dermatopathology, San
Diego, California on 2018 Feb 14-15
Dr. Greta Pandey: Part cipat on in 12
Jude Pediatric Pathology Symposium and viva forum on
March 2018 in Singapore.
Dr. Greta Pandey, Dani Kumar Yadav and Sashi Kushawaha: Training for apheresis and
immunohistochemistry at 4
Hospital, Hebei Medical University, Shijiazhuang, Hebei, People’s
Republic of China from 2018 Aug 13 - Sept 30
Three days training sessions in Usage of RT PCR held at Department of Pathology supported by
American delegates from University of UTAH, USA.
Research and discovery are important missions for the Pathology Department. A broad spectrum of research
act vit es are carried out in the department.
In collaborat on with Berger University Norway, research on the role of S100 protein in Oral
Carcinoma is going on.
1. Dr Sadina Shrestha: Human Papilloma Virus genotype distribut on in cervical cancer biopsies from
Nepalese Women, Infect ous Agents and Cancer 2018,13:4
2. Dr Shankar Bastakot : Angiomyolipoma; a rare ent ty in the lef adrenal gland, Journal of Pathology of
Nepal 2018, Vol 8, 1416-1418.
Head of Department and Senior Consultant:
Dr. Sadina Shrestha, MD
Senior Consultant Pathologist: Dr. Chin Bahadur Pun, MD
Junior Consultant Pathologist: Dr. Ranjan Raj Bhata
Dr Greta Pandey, Dr Shankar Bastakot , Dr Nandita Jha, Dr Suraj Upret , Dr
Asistant Chief Technologist:
Mr. Asta Ram Khagi
Mr. Shyam Sundar Rawal, Mr. Deepak Subedi , Mr. Krishna Pokharel, Mr.
Megh Raj Sapkota , Mr. Dani Kumar Yadav , Mr. Soma Kanta Baral, Mr Pradip
Hamal, Mr. Madan Pandey *.
Mr Rajendra Prasad Joshi, Mr. Keshav Paudel, Mr. Yubaraj Gautam, Ms Srijana
Mr. Asim Shrestha ,Mr. Manohar Shrestha, Ms. Dipa Koirala, Mr. Dipak
Chapagain, Ms.Sushila Adhikari , Mr. Sashi Kushwaha, Ms Chunu Kumari
Tamang, Mr. Gokul Bhandari, Mr Keshav Dhungana, Mr Anil Shah, Ms Binita
ANNUAL REPORT - 2018
Khaitu, Ms Rabika Acharya, Mr Sandip Shah, Mr Uday K. Mandal
Mr. Laxman Bhandari
Ms. Laxmi Neupane,Ms. Sita Dawadi,Ms.Buddhi M. Sunar, Ms.Kalpana
Tamang, Mr. Dhurba Gautam, Ms.Mina Tamang, Ms. Sunita Bhatarai,Ms.
Parbat Aryal, Ms Jamuna Adhikari
Histopathology and cytopathology report ng expedit on through recruitment of Pathologists.
Expansion of immunohistochemistry service and resumpt on of Frozen Sect on.
Expansion of cytogenet cs service and establishment of infrastructure for molecular pathology lab.
Start ng of Clinical-Pathology meet rout nely with Various Clinical Units.
Preparat on of teaching modules for residency based programme, Observat onship and Fellowship.
Set up computerized report ng system and central report dispatch.